Basic Information
VIS ID
TVIS10006736
Fusion event
HBV-LOC112268135 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1788
Integrated sequence
AGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGT| |TGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGC
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh38
Start
25412634 (Hg38)
End
25412634 (Hg38)
Location type
Intronic
Target gene
LOC112268135
Nearest miRNA
hsa-mir-208a/Upstream/1269069; hsa-mir-1185-1/Downstream/1496008;
Nearest TSS
ENST00000550708/Upstream/285636; ENST00000547786/Downstream/730671;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/362228, chr14-CpG: 30/Downstream/792323
Nearby gene
STXBP6(-362337) ;
Downstream sequence
AGTACGGCCGACTCCAGTAGGG
Junction sequence
TTTGTACTAGGAGGCTGTAGAGTACGGCCGACTCCAGTAGGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate