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VISDB
Viral Integration Site DataBase
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TVIS10006737
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006737
Fusion event
HBV-IFNLR1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1808
Integrated sequence
CAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGC| |CATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTT
Host Sequence
Chromosome
chr1
Cytoband
p36.11
Reference genome
GRCh38
Start
24169532 (Hg38)
End
24169532 (Hg38)
Location type
Exon
Fragile sites / regions
FRA1A
Target gene
IFNLR1
miRNAs that regulate target gene
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-6516-5p
;
hsa-mir-455-3p
;
hsa-mir-7847-3p
;
hsa-mir-6880-5p
;
hsa-mir-6851-5p
;
hsa-mir-3689d
;
hsa-mir-6499-3p
;
hsa-mir-508-3p
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-4537
;
hsa-mir-6857-5p
;
hsa-mir-5186
;
hsa-mir-151a-3p
;
hsa-mir-379-5p
;
hsa-mir-3529-5p
;
hsa-mir-4650-3p
;
hsa-mir-3132
;
hsa-mir-197-5p
;
hsa-mir-5187-5p
;
hsa-mir-4450
;
hsa-mir-449b-5p
;
hsa-mir-449a
;
hsa-mir-34c-5p
;
hsa-mir-34a-5p
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-4533
;
hsa-mir-98-5p
;
hsa-mir-4458
;
hsa-mir-4500
;
hsa-let-7i-5p
;
hsa-let-7g-5p
;
hsa-let-7f-5p
;
hsa-let-7e-5p
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-mir-6804-5p
;
hsa-mir-1827
;
hsa-mir-4524a-3p
;
hsa-mir-1252-5p
;
hsa-mir-8089
;
hsa-mir-4700-5p
;
hsa-mir-4667-5p
;
hsa-mir-6831-5p
;
hsa-mir-6755-5p
;
hsa-mir-3927-3p
;
hsa-mir-449c-5p
;
hsa-mir-2682-5p
;
hsa-mir-34b-5p
;
hsa-mir-6876-5p
;
hsa-mir-4476
;
hsa-mir-4463
;
hsa-mir-4499
;
hsa-mir-3154
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-4314
;
hsa-mir-920
;
hsa-mir-6726-5p
;
hsa-mir-5591-5p
;
hsa-mir-4300
;
hsa-mir-6090
;
hsa-mir-6827-5p
;
hsa-mir-6506-5p
;
hsa-mir-3182
;
hsa-mir-619-5p
;
hsa-mir-3192-5p
;
hsa-mir-4646-5p
;
hsa-mir-204-3p
;
hsa-mir-1236-3p
;
hsa-mir-665
;
hsa-mir-4496
;
hsa-mir-548s
;
hsa-mir-4684-5p
;
hsa-mir-4662a-5p
;
hsa-mir-3926
;
hsa-mir-3190-5p
;
hsa-mir-6827-3p
;
hsa-mir-340-3p
;
hsa-mir-6849-3p
;
hsa-mir-3613-3p
;
hsa-mir-575
;
hsa-mir-4676-5p
;
hsa-mir-6858-3p
;
hsa-mir-6771-3p
;
hsa-mir-548c-3p
;
hsa-mir-106a-3p
;
hsa-mir-210-5p
;
hsa-mir-4749-3p
;
hsa-mir-1470
;
hsa-mir-6887-3p
;
hsa-mir-454-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-301b-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-130a-3p
;
hsa-mir-365b-3p
;
hsa-mir-365a-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-1254
;
hsa-mir-1277-3p
;
hsa-mir-140-5p
;
hsa-mir-1915-3p
;
hsa-mir-1976
;
hsa-mir-205-3p
;
hsa-mir-300
;
hsa-mir-3116
;
hsa-mir-3653-3p
;
hsa-mir-3653-5p
;
hsa-mir-3658
;
hsa-mir-3690
;
hsa-mir-381-3p
;
hsa-mir-4254
;
hsa-mir-4426
;
hsa-mir-4434
;
hsa-mir-4516
;
hsa-mir-4531
;
hsa-mir-4534
;
hsa-mir-4647
;
hsa-mir-4662b
;
hsa-mir-485-3p
;
hsa-mir-487a-5p
;
hsa-mir-487b-5p
;
hsa-mir-505-5p
;
hsa-mir-5191
;
hsa-mir-539-3p
;
hsa-mir-5703
;
hsa-mir-6507-5p
;
hsa-mir-6758-5p
;
hsa-mir-6764-5p
;
hsa-mir-6832-5p
;
hsa-mir-6856-5p
;
hsa-mir-6882-5p
;
hsa-mir-8082
;
hsa-mir-1255b-2-3p
;
hsa-mir-1273g-3p
;
hsa-mir-224-3p
;
hsa-mir-4793-3p
;
hsa-mir-522-3p
;
hsa-mir-7703
Nearest miRNA
hsa-mir-12136/Upstream/240385; hsa-mir-101-1/Downstream/749813;
Nearest TSS
ENST00000473358/Upstream/26411;
ENST00000439059/Downstream/17716;
Nearest CpG islands
None/Target,
chr1-CpG: 111/Upstream/189005
,
chr1-CpG: 81/Downstream/17518
Downstream sequence
GCATAGAACATAGCAGCTCCT
Junction sequence
GCATAAATTGGTCTGCGCACGGTGCATAGAACATAGCAGCTCCT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
20
Sample type
Tumor
Age
23
Gender
Female
CpG Island Information
×
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