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VISDB
Viral Integration Site DataBase
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TVIS10006738
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006738
Fusion event
HBV-MED26 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1803
Integrated sequence
AGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTA| |GCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAG
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh38
Start
16582352 (Hg38)
End
16582352 (Hg38)
Location type
Intron
Fragile sites / regions
FRA19B
Target gene
MED26
miRNAs that regulate target gene
hsa-mir-320a
;
hsa-mir-8055
;
hsa-mir-1304-5p
;
hsa-mir-6734-5p
;
hsa-mir-1226-5p
;
hsa-mir-6834-5p
;
hsa-mir-513b-5p
;
hsa-mir-6077
;
hsa-mir-2052
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-6875-5p
;
hsa-mir-3126-5p
;
hsa-mir-4719
;
hsa-mir-9500
Nearest miRNA
hsa-mir-10395/Upstream/1132744; hsa-let-7e/Downstream/1699725;
Nearest TSS
ENST00000633603/Upstream/3575;
ENST00000597226/Downstream/5249;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/9371
,
chr19-CpG: 143/Downstream/45152
Upstream sequence
CCAGGCCCTTTGCAGGGATT
Junction sequence
CCAGGCCCTTTGCAGGGATTCAGACCAATTTATGCCTACA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
20
Sample type
Tumor
Age
23
Gender
Female
CpG Island Information
×
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