Basic Information
VIS ID
TVIS10006739
Fusion event
HBV-chr20 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh38
Start
7007038 (Hg38)
End
7007038 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/3089467; hsa-mir-1-1/Downstream/364570;
Nearest TSS
ENST00000382410/Upstream/239374; ENST00000425900/Downstream/62576;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/236728, chr20-CpG: 96/Downstream/1012104
Nearby gene
BMP2(-226775) ; LINC01428(+139428) ;
Nearest cancer related gene
BMP2(TSG, -226775) ;
Upstream sequence
tctcatacgtatgttaaatttttaaaagtcaaactaatagaagtagcaagtagactggttgttagcagaggctggcagggttgggggaaggtggtagatg
Downstream sequence
aggaaaggaaagatgttggtcaagagtacaaagtttcgattaagagaaataagttgtattgaactatggcacaccatagtgactatagttaacaatattg
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate