VISDB Viral Integration Site DataBase

VIS ID

TVIS10006741

Fusion event

HBV-TTYH3 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1920

Integrated sequence

GTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGA| |TCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACACTTGGCACAGACCTGG

Chromosome

chr7

Cytoband

p22.3

Reference genome

Start

End

2634434 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1296-5p ; hsa-mir-484 ; hsa-mir-218-5p ; hsa-mir-1233-3p ; hsa-mir-4646-3p ; hsa-mir-4433b-5p ; hsa-mir-2355-5p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-150-5p ; hsa-mir-6748-3p ; hsa-mir-339-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-4685-5p ; hsa-mir-6837-5p ; hsa-mir-3620-3p ; hsa-mir-6895-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-656-3p ; hsa-mir-5011-5p ; hsa-mir-6888-5p ; hsa-mir-4428 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-5688 ; hsa-mir-495-3p ; hsa-mir-410-3p ; hsa-mir-143-3p ; hsa-mir-149-3p ; hsa-mir-1914-3p ; hsa-mir-3127-5p ; hsa-mir-3665 ; hsa-mir-3918 ; hsa-mir-4436b-3p ; hsa-mir-4468 ; hsa-mir-4632-5p ; hsa-mir-4728-5p ; hsa-mir-4756-3p ; hsa-mir-4770 ; hsa-mir-5194 ; hsa-mir-564 ; hsa-mir-6088 ; hsa-mir-6735-5p ; hsa-mir-6738-5p ; hsa-mir-6781-5p ; hsa-mir-6785-5p ; hsa-mir-6815-5p ; hsa-mir-6865-5p ; hsa-mir-6879-5p ; hsa-mir-6883-5p ; hsa-mir-7843-5p ; hsa-mir-891a-3p

Nearest miRNA

hsa-mir-339/Upstream/107289; hsa-mir-10399/Downstream/2154131;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/2131, chr7-CpG: 72/Downstream/12505

Upstream sequence

GCCTCCCCTGGTGAGGAGTTGC

Junction sequence