CTNNA1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006745
Fusion event
HBV-CTNNA1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1756
Integrated sequence
TGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGAC| |GTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTC
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
GRCh38
Start
138825876 (Hg38)
End
138825876 (Hg38)
Location type
Intron
Target gene
CTNNA1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-744-5p ; hsa-mir-296-3p ; hsa-mir-769-3p ; hsa-mir-615-3p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10397/Upstream/1178227; hsa-mir-103a-1/Downstream/1737795;
Nearest TSS
ENST00000502646/Upstream/1108; ENST00000524292/Downstream/1751;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/71729, chr5-CpG: 43/Downstream/372305
Upstream sequence
TGGTGCATGTTAAAATTTACTAGC
Junction sequence
TGGTGCATGTTAAAATTTACTAGCAATCTCCTCCCCCAACTCCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate