NKAIN2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006746
Fusion event
HBV-NKAIN2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1825
Integrated sequence
GGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATA| |TTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGC
Host Sequence
Chromosome
chr6
Cytoband
q22.31
Reference genome
GRCh38
Start
124090679 (Hg38)
End
124090679 (Hg38)
Location type
Intron
Target gene
NKAIN2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10398/Upstream/4075422; hsa-mir-1202/Downstream/2393952;
Nearest TSS
ENST00000381078/Upstream/286538; ENST00000546092/Downstream/31171;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/286515, chr6-CpG: 128/Downstream/871299
Downstream sequence
TTCTTCACCTCAGTGAAAC
Junction sequence
CACCAACACCATGCAACTTTTTCTTCACCTCAGTGAAAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate