Basic Information
VIS ID
TVIS10006753
Fusion event
HBV-LINC02327 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1758
Integrated sequence
CGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGT| |AAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCC
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh38
Start
28830705 (Hg38)
End
28830705 (Hg38)
Location type
Intronic
Target gene
LINC02327
Nearest miRNA
hsa-mir-208a/Upstream/1197427; hsa-mir-1185-1/Downstream/2183941;
Nearest TSS
ENST00000550708/Upstream/260; ENST00000550990/Downstream/100865;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/44842, chr14-CpG: 147/Downstream/1096299
Nearby gene
LINC01551(-35911) ; PRKD1(+746532) ;
Upstream sequence
AAGGCAAGAG CAACTTAA
Junction sequence
AAGGCAAGAGCAACTTAATTTAATCTAATCTCCTCCCCC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate