VISDB Viral Integration Site DataBase

VIS ID

TVIS10006755

Fusion event

HBV-PWWP3A integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1816

Integrated sequence

CCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAA| |CGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTA

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

1362666 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1199-5p ; hsa-mir-1225-3p ; hsa-mir-1233-3p ; hsa-mir-125a-5p ; hsa-mir-125b-5p ; hsa-mir-1324 ; hsa-mir-3943 ; hsa-mir-4313 ; hsa-mir-4319 ; hsa-mir-574-3p ; hsa-mir-6751-3p ; hsa-mir-6847-3p

Nearest miRNA

hsa-mir-1302-11/Upstream/549013; hsa-let-7e/Downstream/453493;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/2318, chr19-CpG: 17/Downstream/6149

Nearest cancer related gene

PWWP3A(OG, No orient, 0)

Upstream sequence

GAGTGAGGGATGGCCCAG

Junction sequence