Basic Information
VIS ID
TVIS10006757
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1820
Integrated sequence
AGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGAT| |GTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGA
Host Sequence
Chromosome
chr1
Cytoband
q25.2
Reference genome
GRCh38
Start
179363185 (Hg38)
End
179363185 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-1/Upstream/685351; hsa-mir-1182/Downstream/440739;
Nearest TSS
ENST00000473358/Upstream/68865; ENST00000508229/Downstream/2535;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/68999, chr1-CpG: 47/Downstream/2474
Nearby gene
SOAT1(-4506) ; AXDND1(+2534) ;
Downstream sequence
AGGAAAATAAAGAAAAAAAG
Junction sequence
CTGCGCACCAGCACCATGCACAGCTTGGAGGAAAATAAAGAAAAAAAG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate