Basic Information
VIS ID
TVIS10006763
Fusion event
HBV-chr5 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1827
Integrated sequence
TCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATT| |TGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAG
Host Sequence
Chromosome
chr5
Cytoband
q14.3
Reference genome
GRCh38
Start
91362806 (Hg38)
End
91362806 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/1346086; hsa-mir-103a-1/Downstream/2257890;
Nearest TSS
ENST00000502646/Upstream/7426; ENST00000625713/Downstream/11039;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/81994, chr5-CpG: 89/Downstream/17199
Nearby gene
LUCAT1(-48404) ; ARRDC3(+5917) ;
Upstream sequence
GTCAGGTTCTGCTTCTAACACTA
Junction sequence
GTCAGGTTCTGCTTCTAACACTAAAAAANTTGCANGGTNCTGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate