Basic Information
VIS ID
TVIS10006765
Fusion event
HBV-chr13 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1921
Integrated sequence
TATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGAT| |CGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACACTTGGCACAGACCTGGC
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh38
Start
86522191 (Hg38)
End
86522191 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/8824075; hsa-mir-1267/Downstream/1096474;
Nearest TSS
ENST00000623511/Upstream/461378; ENST00000609962/Downstream/387395;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/2642429, chr13-CpG: 121/Downstream/1149123
Nearby gene
SLITRK6(-722843) ; MIR4500HG(+921795) ;
Downstream sequence
CCAGTCAGAACAGCTGGATATTA
Junction sequence
CATGGACATTGATCCTTATACCAGTCAGAACAGCTGGATATTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate