Basic Information
VIS ID
TVIS10006766
Fusion event
HBV-LOC105370287 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1825
Integrated sequence
GGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATA| |TTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGC
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh38
Start
84077248 (Hg38)
End
84077248 (Hg38)
Location type
Intronic
Target gene
LOC105370287
Nearest miRNA
hsa-mir-1297/Upstream/6379132; hsa-mir-1267/Downstream/3541417;
Nearest TSS
ENST00000623511/Upstream/194855; ENST00000446314/Downstream/485116;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/197486, chr13-CpG: 121/Downstream/3594066
Nearby gene
SLITRK1(-195741) ; LINC00333(+63353) ;
Downstream sequence
CTTCCCAGAGGATAAAAGG
Junction sequence
CACCAGCACCATGCAACTTTCTTCCCAGAGGATAAAAGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate