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VISDB
Viral Integration Site DataBase
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TVIS10006768
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006768
Fusion event
HBV-CD2AP integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1828
Integrated sequence
CGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTT| |GCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGA
Host Sequence
Chromosome
chr6
Cytoband
p12.3
Reference genome
GRCh38
Start
47571362 (Hg38)
End
47571362 (Hg38)
Location type
Intron
Target gene
CD2AP
miRNAs that regulate target gene
hsa-mir-130b-3p
;
hsa-mir-128-3p
;
hsa-mir-124-3p
;
hsa-mir-30b-5p
;
hsa-mir-1-3p
;
hsa-mir-19b-3p
;
hsa-mir-484
;
hsa-mir-186-5p
;
hsa-mir-92a-3p
;
hsa-let-7a-5p
;
hsa-mir-216a-3p
;
hsa-mir-3681-3p
;
hsa-mir-188-5p
;
hsa-mir-491-3p
;
hsa-mir-586
;
hsa-mir-548n
;
hsa-mir-3148
;
hsa-mir-3688-3p
;
hsa-mir-6073
;
hsa-mir-6083
;
hsa-mir-6866-3p
;
hsa-mir-190a-3p
;
hsa-mir-1277-5p
;
hsa-mir-5011-5p
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-15a-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-891b
;
hsa-mir-4517
;
hsa-mir-4524a-5p
;
hsa-mir-4524b-5p
;
hsa-mir-6838-5p
;
hsa-mir-30a-5p
;
hsa-mir-30c-5p
;
hsa-mir-30d-5p
;
hsa-mir-30e-5p
;
hsa-mir-3606-5p
;
hsa-mir-3607-3p
;
hsa-mir-548ao-5p
;
hsa-mir-5585-5p
;
hsa-mir-548ax
;
hsa-mir-551b-5p
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-6074
;
hsa-mir-625-3p
;
hsa-mir-3182
;
hsa-mir-141-5p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-4428
;
hsa-mir-6124
;
hsa-mir-921
;
hsa-mir-6804-3p
;
hsa-mir-3065-3p
;
hsa-mir-376b-3p
;
hsa-mir-376a-3p
;
hsa-mir-4477a
;
hsa-mir-103b
;
hsa-mir-664a-3p
;
hsa-mir-646
;
hsa-mir-503-5p
;
hsa-mir-4789-5p
;
hsa-mir-3941
;
hsa-mir-4797-5p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-548c-3p
Nearest miRNA
hsa-mir-10398/Upstream/2373592; hsa-mir-10524/Downstream/4572987;
Nearest TSS
ENST00000381078/Upstream/37677;
ENST00000463175/Downstream/5151;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/93007
,
chr6-CpG: 44/Downstream/497039
Upstream sequence
CAAAAAGTAGACTGCACAGG
Junction sequence
CAAAAAGTAGACTGCACAGGGAAAAAGTTGCATGGTGCTG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
22
Sample type
Tumor
Age
26
Gender
Female
CpG Island Information
×
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