VISDB Viral Integration Site DataBase

VIS ID

TVIS10006776

Fusion event

HBV-IFRD1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1827

Integrated sequence

TCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATT| |TGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAG

Chromosome

chr7

Cytoband

q31.1

Reference genome

Start

End

112447138 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-30a-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p ; hsa-mir-744-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-6832-5p ; hsa-mir-4451 ; hsa-mir-379-5p ; hsa-mir-3529-5p ; hsa-mir-4650-3p ; hsa-mir-4524a-3p ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-4781-3p ; hsa-mir-1182 ; hsa-mir-4524b-3p ; hsa-mir-7156-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-5096 ; hsa-mir-545-3p ; hsa-mir-6858-3p ; hsa-mir-580-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-3663-3p ; hsa-mir-617 ; hsa-mir-499b-5p ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p

Nearest miRNA

hsa-mir-10525/Upstream/9975607; hsa-mir-10399/Downstream/2206207;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/55012, chr7-CpG: 110/Downstream/2929

Downstream sequence

TGAATCAAAGTCATCAAT

Junction sequence