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VISDB
Viral Integration Site DataBase
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TVIS10006784
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006784
Fusion event
HBV-NCAM2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1783
Integrated sequence
GACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGAT| |CCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTG
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh38
Start
21342520 (Hg38)
End
21342520 (Hg38)
Location type
Intron
Target gene
NCAM2
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-26b-5p
;
hsa-mir-6885-3p
;
hsa-mir-1273e
;
hsa-mir-3591-3p
;
hsa-mir-21-3p
;
hsa-mir-1277-5p
;
hsa-mir-3924
;
hsa-mir-190a-3p
;
hsa-mir-223-5p
;
hsa-mir-511-3p
;
hsa-mir-5011-5p
;
hsa-mir-3065-5p
;
hsa-mir-3529-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-3658
;
hsa-mir-6505-5p
;
hsa-mir-3653-3p
;
hsa-mir-4790-3p
;
hsa-mir-6507-5p
;
hsa-mir-2116-5p
;
hsa-mir-22-5p
;
hsa-mir-26b-3p
;
hsa-mir-3622a-5p
;
hsa-mir-4423-3p
;
hsa-mir-4652-3p
;
hsa-mir-4677-5p
;
hsa-mir-4778-5p
;
hsa-mir-5582-5p
;
hsa-mir-627-3p
;
hsa-mir-6806-5p
Nearest miRNA
hsa-let-7c/Upstream/2656356; hsa-mir-155/Downstream/1736764;
Nearest TSS
ENST00000624081/Upstream/52443;
ENST00000484983/Downstream/121221;
Nearest CpG islands
None/Target,
chr21-CpG: 261/Upstream/344275
,
chr21-CpG: 28/Downstream/4019274
Upstream sequence
AGCCTCTCCAGTATGGCT
Junction sequence
AGCCTCTCCAGTATGGCTTCATACTGGACGGCCTCCTAGTACAAAGACCT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
23
Sample type
Tumor
Age
26
Gender
Female
CpG Island Information
×
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