Basic Information
VIS ID
TVIS10006786
Fusion event
HBV-C9orf92 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1822
Integrated sequence
AAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGT| |ATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATC
Host Sequence
Chromosome
chr9
Cytoband
p22.3
Reference genome
GRCh38
Start
16239119 (Hg38)
End
16239119 (Hg38)
Location type
Intron
Target gene
C9orf92
Nearest miRNA
hsa-mir-101-2/Upstream/10231215; hsa-let-7a-1/Downstream/2334187;
Nearest TSS
ENST00000422679/Upstream/23220; ENST00000430640/Downstream/13995;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/685783, chr9-CpG: 30/Downstream/487742
Downstream sequence
CTGGTGGGAAGTAATTGA
Junction sequence
CAGCACCATGCAACCTGGTGGGAAGTAATTGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate