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VISDB
Viral Integration Site DataBase
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TVIS10006787
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006787
Fusion event
HBV-NTN1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1843
Integrated sequence
GCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAAC| |AGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTT
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh38
Start
9077821 (Hg38)
End
9077821 (Hg38)
Location type
Intron
Target gene
NTN1
miRNAs that regulate target gene
hsa-mir-148b-3p
;
hsa-mir-1296-5p
;
hsa-mir-423-3p
;
hsa-mir-486-3p
;
hsa-mir-6780b-5p
;
hsa-mir-4271
;
hsa-mir-4725-3p
;
hsa-mir-7106-5p
;
hsa-mir-765
;
hsa-mir-2467-3p
;
hsa-mir-6133
;
hsa-mir-6130
;
hsa-mir-6129
;
hsa-mir-6127
;
hsa-mir-4510
;
hsa-mir-4419a
;
hsa-mir-6805-5p
;
hsa-mir-6783-5p
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-1321
;
hsa-mir-4779
;
hsa-mir-6873-5p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-4749-3p
;
hsa-mir-4313
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-6887-3p
;
hsa-mir-361-3p
;
hsa-mir-6769a-3p
Nearest miRNA
hsa-mir-1253/Upstream/890817; hsa-mir-10226/Downstream/3004078;
Nearest TSS
ENST00000595228/Upstream/56279;
ENST00000436734/Downstream/85114;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/54218
,
chr17-CpG: 23/Downstream/37858
Downstream sequence
CTAAGCGGATGAGGCAGG
Junction sequence
AGTAGGACATGAACAAGAGATCTAAGCGGATGAGGCAGG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
23
Sample type
Tumor
Age
26
Gender
Female
CpG Island Information
×
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