hsa-mir-6844 _LIHC.png
ROBO2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006794
Fusion event
HBV-ROBO2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1809
Integrated sequence
AAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCC| |ATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTC
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh38
Start
76457907 (Hg38)
End
76457907 (Hg38)
Location type
Intronic
Target gene
ROBO2
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-342-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-6844 ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-8084
Nearest miRNA
hsa-let-7g/Upstream/719544; hsa-mir-12124/Downstream/3049980;
Nearest TSS
ENST00000440867/Upstream/146811; ENST00000471893/Downstream/581979;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/550750, chr3-CpG: 63/Downstream/581440
Nearby gene
ZNF717(-672324) ; ROBO2(+582235) ;
Upstream sequence
GGTTGGGGCGACTGGGACACAG
Junction sequence
GGTTGGGGCGACTGGGACACAGGGTGCGCACACCAATTTATG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate