Basic Information
VIS ID
TVIS10006795
Fusion event
HBV-LOC105374786 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1798
Integrated sequence
GAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACA| |GCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCG
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh38
Start
67602716 (Hg38)
End
67602716 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105374786
Nearest miRNA
hsa-mir-1301/Upstream/1244388; hsa-mir-10b/Downstream/1500966;
Nearest TSS
ENST00000437798/Upstream/40649; ENST00000430742/Downstream/81361;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/205004, chr2-CpG: 70/Downstream/554336
Nearby gene
ETAA1(-192315) ; LINC01812(+193337) ;
Upstream sequence
GATAGAGATATAAAATTCTG
Junction sequence
GATAGAGATATAAAATTCTGCAATTTATGCCTACAGCCTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate