ZCCHC7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006796
Fusion event
HBV-ZCCHC7 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1798
Integrated sequence
GAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACA| |GCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCG
Host Sequence
Chromosome
chr9
Cytoband
p13.2
Reference genome
GRCh38
Start
37277108 (Hg38)
End
37277108 (Hg38)
Location type
Intron
Target gene
ZCCHC7
miRNAs that regulate target gene
hsa-mir-365a-3p
Nearest miRNA
hsa-mir-101-2/Upstream/383577; hsa-let-7a-1/Downstream/3651902;
Nearest TSS
ENST00000422679/Upstream/132176; ENST00000463625/Downstream/7055;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/156120, chr9-CpG: 44/Downstream/145463
Upstream sequence
CCAAGTATAGACTCATT
Junction sequence
CCAAGTATAGACTCATTCAATTTATGCCTACTGCCTC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate