VISDB Viral Integration Site DataBase

VIS ID

TVIS10006799

Fusion event

HBV-LMBR1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1819

Integrated sequence

GAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGA| |TGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGG

Chromosome

chr7

Cytoband

q36.3

Reference genome

Start

End

156783566 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-21-5p ; hsa-mir-548j-3p ; hsa-mir-548x-3p ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-519d-5p ; hsa-mir-3613-3p ; hsa-mir-3145-5p ; hsa-mir-4677-5p ; hsa-mir-22-5p ; hsa-mir-2116-5p ; hsa-mir-4719 ; hsa-mir-4698 ; hsa-mir-3646 ; hsa-mir-3662 ; hsa-mir-4693-3p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-4506

Nearest miRNA

hsa-mir-10399/Upstream/5349927; hsa-mir-153-2/Downstream/790770;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/142590, chr7-CpG: 65/Downstream/109325

Downstream sequence

GACTGTGTCTATCATTGGGTTG

Junction sequence