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VISDB
Viral Integration Site DataBase
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TVIS10006801
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006801
Fusion event
HBV-SLC30A8 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1778
Integrated sequence
CGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGC| |AGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACC
Host Sequence
Chromosome
chr8
Cytoband
q24.11
Reference genome
GRCh38
Start
117071845 (Hg38)
End
117071845 (Hg38)
Location type
Intron
Target gene
SLC30A8
Nearest miRNA
hsa-mir-12123/Upstream/197045; hsa-mir-10400/Downstream/2253326;
Nearest TSS
ENST00000518652/Upstream/120894;
ENST00000518396/Downstream/62963;
Nearest CpG islands
None/Target,
chr8-CpG: 109/Upstream/133125
,
chr8-CpG: 45/Downstream/448771
Upstream sequence
AGATTTACCATTTTAATAAACATG
Junction sequence
AGATTTACCATTTTAATAAACATGCTAGTACAAAGACCTTTAAT
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
26
Sample type
Tumor
Age
29
Gender
Female
CpG Island Information
×
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