Basic Information
VIS ID
TVIS10006803
Fusion event
HBV-chr6 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1813
Integrated sequence
GACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGG| |AAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCA
Host Sequence
Chromosome
chr6
Cytoband
q16.3
Reference genome
GRCh38
Start
103795610 (Hg38)
End
103795610 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/4670914; hsa-mir-1202/Downstream/2988515;
Nearest TSS
ENST00000381078/Upstream/1867467; ENST00000635857/Downstream/936760;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/2392512, chr6-CpG: 79/Downstream/1063634
Nearby gene
HACE1(+932482) ;
Nearest cancer related gene
HACE1(TSG, +932482) ;
Downstream sequence
AAAGAAAAAAAAACCCTATGG
Junction sequence
AATTGGTCTGCGCACCAGCAAAAGAAAAAAAAACCCTATGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate