FGF14 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006804
Fusion event
HBV-FGF14 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1806
Integrated sequence
CCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCA| |GCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAG
Host Sequence
Chromosome
chr13
Cytoband
q33.1
Reference genome
GRCh38
Start
102146298 (Hg38)
End
102146298 (Hg38)
Location type
Intron
Target gene
FGF14
miRNAs that regulate target gene
hsa-mir-574-5p ; hsa-mir-4455 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-8068
Nearest miRNA
hsa-mir-1297/Upstream/100294; hsa-mir-1267/Downstream/5384873;
Nearest TSS
ENST00000623511/Upstream/229653; ENST00000444686/Downstream/221241;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/229173, chr13-CpG: 60/Downstream/248032
Downstream sequence
TGGTGGCTGACAAATTATTTT
Junction sequence
AGGCATAAATTGGTCTGCGCTGGTGGCTGACAAATTATTTT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
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