Basic Information
VIS ID
TVIS10006806
Fusion event
HBV-LINC02542 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1850
Integrated sequence
CGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTA| |TCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCA
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh38
Start
81890783 (Hg38)
End
81890783 (Hg38)
Location type
Intronic
Target gene
LINC02542
Nearest miRNA
hsa-mir-10398/Upstream/3351474; hsa-mir-1202/Downstream/8421959;
Nearest TSS
ENST00000381078/Upstream/76626; ENST00000535040/Downstream/42697;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/136695, chr6-CpG: 49/Downstream/356499
Nearby gene
LINC01526(-76591) ; IBTK(+279455) ;
Downstream sequence
ACCACACACGGTCAAACAA
Junction sequence
CCTCTGCCTAATCATCTCTTGACCACACACGGTCAAACAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate