VISDB Viral Integration Site DataBase

VIS ID

TVIS10006814

Fusion event

HBV-NKAIN1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1799

Integrated sequence

AGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAG| |CCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGG

Chromosome

chr1

Cytoband

p35.2

Reference genome

Start

End

31238043 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-129-5p ; hsa-mir-219a-1-3p ; hsa-mir-3174 ; hsa-mir-3976 ; hsa-mir-432-3p ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-4693-3p ; hsa-mir-496 ; hsa-mir-5004-3p ; hsa-mir-5192 ; hsa-mir-5586-3p ; hsa-mir-571 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6731-5p ; hsa-mir-6744-5p ; hsa-mir-6758-5p ; hsa-mir-6760-5p ; hsa-mir-6856-5p ; hsa-mir-6873-5p ; hsa-mir-7850-5p ; hsa-mir-8085

Nearest miRNA

hsa-mir-12136/Upstream/498811; hsa-mir-101-1/Downstream/520617;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/56057, chr1-CpG: 78/Downstream/1188

Downstream sequence

CCTCTGCAATCCTCAGGGATA

Junction sequence