Basic Information
VIS ID
TVIS10006818
Fusion event
HBV-LOC105374951 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1819
Integrated sequence
GAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGA| |TGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGG
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh38
Start
17025890 (Hg38)
End
17025890 (Hg38)
Location type
Intronic
Target gene
LOC105374951
Nearest miRNA
hsa-mir-3691/Upstream/884266; hsa-mir-10398/Downstream/1545894;
Nearest TSS
ENST00000381078/Upstream/261544; ENST00000354384/Downstream/76368;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/263136, chr6-CpG: 34/Downstream/76188
Nearby gene
ATXN1(-264400) ; STMND1(+76367) ;
Upstream sequence
TGCCATGCTGGGTTTCA
Junction sequence
TGCCATGCTGGGTTTCAGCATGGTGCTGGTGCGCAGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate