VISDB Viral Integration Site DataBase

VIS ID

TVIS10006821

Fusion event

HBV-PREX2 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2015

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

1815

Chromosome

chr8

Cytoband

q13.2

Reference genome

Start

End

68003916 (Hg38)

Orient

+

Location type

Intronic 1

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-338-3p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-219b-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p

Nearest miRNA

hsa-mir-124-1/Upstream/3622962; hsa-mir-10400/Downstream/6544627;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/49508, chr8-CpG: 75/Downstream/326769

Upstream sequence

TAATTTTGCCTTTTTTTCtttttctttctttctttcttttttttttgaggtggagtctcgctgtgccatctaggctggaatgcagtggcatgatcttggt

Downstream sequence

cggctcactgcaacgtctgcctcccccgttccagcgattctcctgcctcagcctcccaagtagctgggactacaggcgtgtggcacgtgccactacacct

Target sequence

tctctgcaacttgcacctcctaggttcaagtgattctcatgcctcagcctcctgagtagctgggattataggtgtgtgccatcacacccggctaatttttgtattttagtagagatagtgttttgccatgttggccaggctggtctttaactcctgacctcaactgatactcctgcctcggtctcccaaagtgctgggattacTCCCACCTCCATCTCACAAAGTGCTCTCCCAAAGGCGTGAGCCACTGTGCCT