Basic Information
VIS ID
TVIS10006824
Fusion event
HBV-chr4:q12 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2015
PubMed ID
25815780
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1621
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh38/hg38
Start
52251977 (Hg38)
End
52252646 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-12113/Upstream/4599234; hsa-mir-1243/Downstream/460036;
Nearest TSS
ENST00000502981/Upstream/173633; ENST00000503051/Downstream/375720;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/174895, chr4-CpG: 141/Downstream/406151
Upstream sequence
tgagtattgcaaaggaagaaatctttaatcaggtcctgtagccaaggagatgaaagatcagtctcaaatccatctccctgcctgactaaaattgcgggtt
Downstream sequence
catcaggtcccctggttctcaggcctctggtctcagacttaattgtacctctagcttccctggttttccagcttgcagattgtgggacttctcagccttt
Target sequence
taaatagcagggaagaaatgtaaccatgtgtgggaagacaggaataagggcagggtaaggaagaggagttggtcaataggaagcagatggtcagttaggcaatcatgacgggtgagggatctgatgtctcattgtccaaatgcagtgatctaatgagtttcagctccttgatactatctaggagtcctgatggttggttttctgagaaaggaactcagataagaaaaattaagctttcttaagttttaagactgg
Reference
Zhang, X., et al. DNA methylation consistency implicates the primary tumor cell origin of recurrent hepatocellular carcinoma. Epigenomics,2015, 7(4): 581-592.
Curate