Basic Information
VIS ID
TVIS10006827
Fusion event
HBV-chr19:p13.11 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2015
PubMed ID
25815780
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
1486
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh38/hg38
Start
17041317 (Hg38)
End
17041506 (Hg38)
Orient
-
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/1591709; hsa-let-7e/Downstream/1240571;
Nearest TSS
ENST00000633603/Upstream/14502; ENST00000598893/Downstream/10488;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/14045, chr19-CpG: 118/Downstream/33727
Nearby gene
HAUS8(+8444) ;
Upstream sequence
accggttaatttttgtattttactggagacagagtttcaccatgttggccaggctggtcttgaactcctggcctcaagtgatccacctgcctcggcctcc
Downstream sequence
gttgtattttttaagtagagatggggtttcaccgtgttagccaggatggtctccatctcctgacctcgtgatccacccacctcggcctcctaaagtgctg
Target sequence
caaagtgctgggattacaggtgtgagccaccatgcccagcctcttttttttttttttttttgaggcagagtcagtggcgcaatctcggctcactgcaagctccgcctcccgggttcacgccattctcctgcctcaccctcctgagtagctgggactacagccgcccgccaccacacccggctaattttt
Reference
Zhang, X., et al. DNA methylation consistency implicates the primary tumor cell origin of recurrent hepatocellular carcinoma. Epigenomics,2015, 7(4): 581-592.
Curate