VISDB Viral Integration Site DataBase

VIS ID

TVIS10006828

Fusion event

HBV-ANKRD36 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2015

PubMed ID

Virus name

HBV

Reference genome

Not given

Start

1786

Chromosome

chr2

Cytoband

q11.2

Reference genome

Start

End

97244162 (Hg38)

Orient

+

Location type

Intronic 69

Fragile sites / regions

FRA2S ; FRA2A

Target gene

miRNAs that regulate target gene

hsa-mir-6079 ; hsa-mir-6077 ; hsa-mir-7-5p ; hsa-mir-7515 ; hsa-mir-3154 ; hsa-mir-4661-5p ; hsa-mir-376c-3p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-96-5p ; hsa-mir-1271-5p ; hsa-mir-182-5p ; hsa-mir-183-5p ; hsa-mir-2355-5p ; hsa-mir-593-5p ; hsa-mir-6849-3p ; hsa-mir-3976 ; hsa-mir-6838-5p ; hsa-mir-4274 ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-640 ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-4680-5p ; hsa-mir-4635 ; hsa-mir-3663-5p ; hsa-mir-4793-3p ; hsa-mir-3653-5p ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-5698 ; hsa-mir-1178-3p ; hsa-mir-6794-3p ; hsa-mir-891a-3p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-564 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-3934-3p ; hsa-mir-6499-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-5693 ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-4639-3p ; hsa-mir-3155a ; hsa-mir-3664-5p

Nearest miRNA

hsa-mir-1285-2/Upstream/445252; hsa-mir-10b/Downstream/4065288;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/129802, chr2-CpG: 113/Downstream/345495

Upstream sequence

atcccctggatctgcatagaaaggaaggaaaacaaaggggaaagggggttctctatagaatgtggatttttcccacaagagactttgcagggcaatttca

Downstream sequence

CATTTATAGCTATAATTATTTATAATAAACCTTGAAATATTTTATTTTAGTTCAAAGGCCTTTTGAAAACAATGCTATTCTACAATATATACTTAATGAT

Target sequence

aggcatggcaaggaaatatattttggattaaatattttcttccttgtctcgtaaggttatgccagagtcagattgaaaagcaagtcacaatatacagggtcaaataaaacccatctgatgagaatccatggtttgtagggcacgactccctggaccccttaggtaggaatttgggcaagataaaaaattagagcttagtcctcaCTGATAAGATAAATTCTAAGATAAGTATATTTACAGATTTGCCATACAGCA