Basic Information
VIS ID
TVIS10006830
Fusion event
HBV-chr20:p12.3 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2015
PubMed ID
25815780
Virus Sequence
Virus name
HBV
Reference genome
Not given
Start
2230
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh38/hg38
Start
5639689 (Hg38)
End
5640155 (Hg38)
Orient
-
Nearest miRNA
hsa-mir-103a-2/Upstream/1722118; hsa-mir-1-1/Downstream/1731453;
Nearest TSS
ENST00000382410/Upstream/28663; ENST00000378979/Downstream/110238;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/28460, chr20-CpG: 57/Downstream/271077
Upstream sequence
agacggggtggcggccgggcagaggctgcaatctcggcactttgggaggccaaggcaggcggctgggaggtggaggttgtagcgagccgagatcacgcta
Downstream sequence
ggctggttttctcttttcaagtacttttccacatggctaaattgggcttccttacaacatggtgggttaaagagaatcacacatctcacatggtaactgg
Target sequence
ctgcactccagcctgggcaccattgagcactgagtgaacgagactccgtctgcaatcccggcacctcgggaggccgaggctggcggatcactcgcggtcaggagctggagaccagcccggccaacacagggaaaccctgtctccaccaaaacaatacgaaaaccagtcaggcgtggcggcgcgcgcctgcaatcgcaggcactcggcaggctgaggcaggagaatcaggcagggaggttgcagtgagcagagatg
Reference
Zhang, X., et al. DNA methylation consistency implicates the primary tumor cell origin of recurrent hepatocellular carcinoma. Epigenomics,2015, 7(4): 581-592.
Curate