VISDB Viral Integration Site DataBase

VIS ID

TVIS10006834

Fusion event

HBV-LRIF1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

Polymerase,Pre-S1/S2/S,S

Start

2984

Integrated sequence

GGACAAATCTTTCTGTCCCCAATCCCCTGGGATTCTTCCCCGATCATCAGTTGGACCCTGCATTCAAAGCCAACTCAGAAAATCCAGATTGGGACCTCAA| |CCCGCACAAGGACAACTGGCCGGACGCCAACAAGGTGGGAGTGGGAGCATTCGGGCCAGGGTTCACCCCTCCCCATGGGGGACTGTTGGGGTGGAGCCCT

Chromosome

chr1

Cytoband

p13.3

Reference genome

Start

End

111480460/110937838 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-4310 ; hsa-mir-7157-5p ; hsa-mir-4668-5p ; hsa-mir-3152-5p ; hsa-mir-6514-3p ; hsa-mir-4774-3p ; hsa-mir-6894-3p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-186-3p ; hsa-mir-3613-3p ; hsa-mir-5588-3p ; hsa-mir-548e-5p ; hsa-mir-1258 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6739-3p ; hsa-mir-3658 ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-2117 ; hsa-mir-4273 ; hsa-mir-5193 ; hsa-mir-660-3p ; hsa-mir-4279 ; hsa-mir-6882-3p ; hsa-mir-4524a-3p ; hsa-mir-7157-3p ; hsa-mir-6737-3p ; hsa-mir-5008-3p ; hsa-mir-1304-3p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-1182 ; hsa-mir-4524b-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4252 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-1273g-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-576-3p ; hsa-mir-5683 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1338871; hsa-mir-11399/Downstream/1523932;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/157027, chr1-CpG: 87/Downstream/25421

Nearby gene

Upstream sequence

gaaattgaaatagagaaaatacaaaagatcaatgaaacaaaatggttttttgaaaagttaaacaaaatttacaaacctttagccagactaagaagaaaaa

Downstream sequence

aggagacacaaattaataaaatcagaaatgaaaaaggagcattacaactgatactgcagaaattcaaaggatcattagaggctactatgagcaactatat