Basic Information
VIS ID
TVIS10006837
Fusion event
HBV-chr14 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
Polymerase,Pre-S1/S2/S,S
Start
2984
Integrated sequence
GGACAAATCTTTCTGTCCCCAATCCCCTGGGATTCTTCCCCGATCATCAGTTGGACCCTGCATTCAAAGCCAACTCAGAAAATCCAGATTGGGACCTCAA| |CCCGCACAAGGACAACTGGCCGGACGCCAACAAGGTGGGAGTGGGAGCATTCGGGCCAGGGTTCACCCCTCCCCATGGGGGACTGTTGGGGTGGAGCCCT
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37/hg19
Start
28563411/28094205 (Hg38)
End
28563411/28094205 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/460927; hsa-mir-1185-1/Downstream/2920441;
Nearest TSS
ENST00000550708/Upstream/460080; ENST00000548280/Downstream/223936;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1888933, chr14-CpG: 203/Downstream/671478
Nearby gene
FOXG1(No orient, 672876)
Nearest cancer related gene
FOXG1(OG, No orient, 672876)
Upstream sequence
tatattgatgagccaatagtcatatcatataaattagggtatatttctaacactgggaatgtgtcttccaactcaattcttaaagtttataattttggct
Downstream sequence
cttctctagtttttgaatttccatgtaagtgtaaattatcttctgaatattcacaagtaaatgctggtagaatattttatctggattgcattgaatatat
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate