ME1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006838
Fusion event
HBV-ME1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
Polymerase,S
Start
835
Integrated sequence
TATATGGATGATGTGGTTTTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTATGCCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAA| |ACCCTCACAAAACAAAAAGATGGGGATATTCCCTTAACTTCATGGGATATGTAATTGGGAGTTGGGGCACATTGCCACAGGAACATATTGTACAAAAAAT
Host Sequence
Chromosome
chr6
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
83965334/83255615 (Hg38)
End
83965334/83255615 (Hg38)
Location type
Intronic
Target gene
ME1
miRNAs that regulate target gene
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-10398/Upstream/4716306; hsa-mir-1202/Downstream/7057127;
Nearest TSS
ENST00000381078/Upstream/61679; ENST00000369700/Downstream/175456;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/61557, chr6-CpG: 60/Downstream/175078
Upstream sequence
gcaaagcattcaaaatgtgacttgggtgctgttaaaggcattcagctttataagggaagtaaaggataaaagttcaaaattttgcagcctgacaatgtga
Downstream sequence
aaatttctgttttctatataatcacccaactatgtcagcaccatttatttaacagtccatccttctcctcatcacctataattagatactatattctgat
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate