VISDB Viral Integration Site DataBase

VIS ID

TVIS10006839

Fusion event

HBV-ANK1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

Polymerase

Start

1138

Integrated sequence

GGATATCCTGCTTTAATGCCTTTATATGCATGTATACAAGCAAAACAGGCTTTTACTTTCTCGCCAACTTACAAGGCCTTTCTAAGTAAACAGTATCTGA| |ACCTTTACCCCGTTGCTCGGCAACGGCCTGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCATAGGCCATCAGCGCATGCG

Chromosome

chr8

Cytoband

p11.21

Reference genome

Start

End

41554277/41696759 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-513b-5p ; hsa-mir-597-5p ; hsa-mir-6747-5p ; hsa-mir-7110-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-206 ; hsa-mir-613 ; hsa-mir-1-3p ; hsa-mir-125b-2-3p ; hsa-mir-4457 ; hsa-mir-4802-5p ; hsa-mir-6732-5p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-663b ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-7106-5p ; hsa-mir-6825-5p ; hsa-mir-874-5p ; hsa-mir-6894-5p ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-3605-5p ; hsa-mir-1204 ; hsa-mir-1247-3p ; hsa-mir-5587-3p ; hsa-mir-6840-5p ; hsa-mir-2392 ; hsa-mir-1273e ; hsa-mir-4709-3p ; hsa-mir-4684-5p ; hsa-mir-4635 ; hsa-mir-942-5p ; hsa-mir-877-3p ; hsa-mir-376c-3p ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-202-3p

Nearest miRNA

hsa-mir-124-1/Upstream/36251; hsa-mir-10400/Downstream/1199438;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/42568, chr8-CpG: 29/Downstream/4978

Upstream sequence

TATGAAAATTGAAAAGAATTTATGAAAATTGAAAAGAATATGAAATTATGAAAATAATTTTGTATGATCAGAAATAATGTCtaaatatctatgacactta

Downstream sequence

TACTCTTTAGATGCCTGAGGAGAGAGAAAGGGTCCTCCTGTCCCACCTCCTCCCGGGCCAGCTGGATGCCGTGCCAGGGCGTGGAGGCTTGGAAGAACCT