Basic Information
VIS ID
TVIS10006843
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase,S
Start
409
Integrated sequence
TTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTATCGCTGGATGTGTCTGCGGCGTTTTATCATATTCCTCTTC| |ATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTGTCCTCTACTTCCAGGAACATCAACTACCAGCACGG
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
10360/10360 (Hg38)
End
10360/10360 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-101-1/Downstream/7009;
Nearest TSS
ENST00000473358/Downstream/19194;
Nearest CpG islands
None/Target, None/Upstream, chr1-CpG: 111/Downstream/18375
Nearby gene
DDX11L1
Upstream sequence
taaccctaaccctaaccctaaccctaaccccaaccccaaccccaaccccaaccccaaccccaaccctaacccctaaccctaaccctaaccctaccctaac
Downstream sequence
cctaaccctaaccctaaccctaaccctaacccctaacccctaaccctaaccctaaccctaaccctaaccctaaccctaacccctaaccctaaccctaacc
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
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