Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006850
Fusion event
HBV-CTNNA2 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
Region type
Polymerase,S
Start
704
Integrated sequence
CCCATCCCATCATCTTGGGCTTTCGCAAAATACCTATGGGAGTGGGCCTCAGTCCGTTTCTCTTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCG| |TAGGGCTTTCCCCCACTGTCTGGCTTTCAGTTATATGGATGATGTGGTTTTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTATGCCGCTGTTACC
Host Sequence
Chromosome
chr2
Cytoband
p12
Reference genome
Start
End
80612761/80385636 (Hg38)
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/519053; hsa-mir-10b/Downstream/5397964;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/62963, chr2-CpG: 93/Downstream/808444
Nearest cancer related gene
CTNNA2(TSG, No orient, 0)
Upstream sequence
agctcaaatgaattaTTAATAAAAGAACACATAATGGAAAATATGAACCATTTTGATTTGACTCCAAAAGCTGActtctcttttcttcccctccttcttc
Downstream sequence
ttcccttaaatttctttttctccaattcttcatccctttcttGCCGCAGTTTCTCTCATCATCTCTCCCTCctgtctctctgtctttctccgtcttcctc
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.