VISDB Viral Integration Site DataBase

VIS ID

TVIS10006854

Fusion event

HBV-SLC47A1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

pre-core/core

Start

1882

Integrated sequence

GTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGC| |CTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTC

Chromosome

chr17

Cytoband

p11.2

Reference genome

Start

End

19451827/19548514 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6770-3p ; hsa-mir-4730 ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3144-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4467 ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-8072 ; hsa-mir-3960 ; hsa-mir-1307-3p ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-6784-5p ; hsa-mir-4655-5p ; hsa-mir-4665-5p ; hsa-mir-5010-5p ; hsa-mir-1275 ; hsa-mir-4525 ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-6883-5p ; hsa-mir-6825-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-3616-3p ; hsa-mir-4680-5p ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-4700-5p ; hsa-mir-8089 ; hsa-mir-4667-5p ; hsa-mir-330-5p ; hsa-mir-326 ; hsa-mir-181d-3p ; hsa-mir-514a-5p ; hsa-mir-5008-5p ; hsa-mir-6851-3p ; hsa-mir-7160-3p

Nearest miRNA

hsa-mir-1180/Upstream/203940; hsa-mir-10226/Downstream/7745396;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/14135, chr17-CpG: 58/Downstream/31399

Upstream sequence

tattcttgaccttcgttgatattaaaatcacctgggtgctttcaaacccacctgtgcccctgctccctaccacccaagatttttcttttttttttttttt

Downstream sequence

tttgagaccaagtctcactccgtcccccagactggaatgcagtggtgcgatcttggctcgctgcaacctctgcctcctgggttcaagcaattctcctgcc