Basic Information
VIS ID
TVIS10006856
Fusion event
HBV-LINC01676 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
pre-core/core
Start
1882
Integrated sequence
GTAGGCATAAATTGGTGTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGC| |CTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTC
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
106151059/105608437 (Hg38)
End
106151059/105608437 (Hg38)
Location type
Intronic
Target gene
LINC01676
Nearest miRNA
hsa-mir-101-1/Upstream/5327129; hsa-mir-11399/Downstream/2288786;
Nearest TSS
ENST00000473358/Upstream/2430; ENST00000635102/Downstream/10438;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/2082146, chr1-CpG: 37/Downstream/472334
Upstream sequence
aaccaaatgaaagtcaatatagctaaggtatggagagttacaggaatagatacgtgaaaagatcctagaaagttagacagaaagaaacccctggatggta
Downstream sequence
ttattggctagattttgggtctgttcaaatatcactaggaaggccttgaattgttctatacatcagatgaccatcagttttacatttacaaaaggagatc
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate