VISDB Viral Integration Site DataBase

VIS ID

TVIS10006859

Fusion event

HBV-GOLGA7 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

pre-core/core

Start

2279

Integrated sequence

GGCCTAAAAATCAGACAACTATTGTGGTTTCACATTTCCTGTCTTACTTTTGGGAGAGAAACTGTTCTTGAATATTTGGTGTCTTTTGGAGTGTGGATTC| |GCACTCCTCCTGCATATAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGAAACTACTGTTGTTAGACGAAGAGGCAGGTCCCCTAGAAGAAGAAC

Chromosome

chr8

Cytoband

p11.21

Reference genome

Start

End

41350157/41492638 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-124-3p ; hsa-mir-186-5p ; hsa-mir-191-5p ; hsa-mir-16-5p ; hsa-mir-922 ; hsa-mir-6868-5p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-338-5p ; hsa-mir-5682 ; hsa-mir-6871-3p ; hsa-mir-548c-3p ; hsa-mir-3162-5p ; hsa-mir-760 ; hsa-mir-8057 ; hsa-mir-5691 ; hsa-mir-6805-3p ; hsa-mir-6822-3p ; hsa-mir-885-3p ; hsa-mir-3194-3p ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-3128 ; hsa-mir-1322 ; hsa-mir-585-5p ; hsa-mir-770-5p ; hsa-mir-4712-5p ; hsa-mir-16-1-3p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-let-7f-2-3p ; hsa-mir-6757-5p ; hsa-mir-101-3p ; hsa-mir-1277-5p ; hsa-mir-144-3p

Nearest miRNA

hsa-mir-124-1/Upstream/221495; hsa-mir-10400/Downstream/167803;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/1576, chr8-CpG: 52/Downstream/36291

Upstream sequence

agatcatagtttggttctataacatgaacagtcctatattttgccacttaatgctacatatgcaaaagtttctttaagctgatatctaagagcaaaatgg

Downstream sequence

gcgacagagcaagactcttgtctcaaaaaataaatcaaataaaaaGATATACATGGAATCAATCAAATGTTTTATTTTTAAGCCTCTTACGGAAACTATG