VISDB Viral Integration Site DataBase

VIS ID

TVIS10006862

Fusion event

HBV-FN1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

X protein

Start

2010

Integrated sequence

ACCCGTATAAAGAATTTGGAGCTTCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCT| |GTATCGGGAGGCCTTAGAGTCTCCGGAACATTGTTCACCTCACCATACAGCACTCAGGCAAGCTATTCTGTGTTGGGGTGAGTTGATGAATCTGGCCACC

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216248136/215383413 (Hg38)

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1625254; hsa-mir-1244-1/Downstream/2517100;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/71004, chr2-CpG: 43/Downstream/52131

Upstream sequence

CAGATGATTCTTACCTGGACCTGCAGTTTTAGTTTTTGTTGGTCCTGGTCCATTTTTGGGAGTGGTGGTTACTCTGTAACCAGTAACAGGGGAACTTGAA

Downstream sequence

GGCAGCCACTTGACACTAATGCTGTTGTCCTGAACATCGGTCACTTGCATCTGGGATGGTTTGTCAATTTCTACAAATAAAAGCAGGGAGAAACCAGTGA