Basic Information
VIS ID
TVIS10006863
Fusion event
HBV-LOC105370287 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
Polymerase,S
Start
1710
Integrated sequence
GAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCA| |AAGACTGTGTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGC
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
84655780/84081645 (Hg38)
End
84655780/84081645 (Hg38)
Location type
Intronic
Target gene
LOC105370287
Nearest miRNA
hsa-mir-1297/Upstream/6383529; hsa-mir-1267/Downstream/3537020;
Nearest TSS
ENST00000623511/Upstream/199252; ENST00000446314/Downstream/480719;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/201883, chr13-CpG: 121/Downstream/3589669
Nearby gene
SLITRK1(No orient, 1711142)
Upstream sequence
AGTTTATTTTCTTGAATTTTTCTTCTTCACTCACGCTTCTCATTGAATAACTCAGAAAATTAAAACATTCTTCTGAATACTCACAGTAAAACAACCATGT
Downstream sequence
CTGATTAAATCTCTGATGCATTGAAGTTAGAAGAGACCCAATATCAAATCTAGATTAACCAGCATCTTACTTATTTTAGATAGAGCTTCATCGTGTTGTG
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
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