VISDB Viral Integration Site DataBase

VIS ID

TVIS10006864

Fusion event

HBV-LRIF1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

Polymerase

Start

370

Integrated sequence

CAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTAT| |CGCTGGATGTGTCTGCGGCGTTTTATCATATTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCG

Chromosome

chr1

Cytoband

p13.3

Reference genome

Start

End

111480380/110937758 (Hg38)

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-4310 ; hsa-mir-7157-5p ; hsa-mir-4668-5p ; hsa-mir-3152-5p ; hsa-mir-6514-3p ; hsa-mir-4774-3p ; hsa-mir-6894-3p ; hsa-mir-661 ; hsa-mir-3116 ; hsa-mir-1254 ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-186-3p ; hsa-mir-3613-3p ; hsa-mir-5588-3p ; hsa-mir-548e-5p ; hsa-mir-1258 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6739-3p ; hsa-mir-3658 ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-2117 ; hsa-mir-4273 ; hsa-mir-5193 ; hsa-mir-660-3p ; hsa-mir-4279 ; hsa-mir-6882-3p ; hsa-mir-4524a-3p ; hsa-mir-7157-3p ; hsa-mir-6737-3p ; hsa-mir-5008-3p ; hsa-mir-1304-3p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-1182 ; hsa-mir-4524b-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-4252 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-1273g-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-576-3p ; hsa-mir-5683 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1338791; hsa-mir-11399/Downstream/1524012;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/156947, chr1-CpG: 87/Downstream/25501

Upstream sequence

tcttaaagaactagaaaagcaagagcaaacctcacccaaaattagtagaagaaaagaaataataaagagcagaaataaatgaaattgaaatagagaaaat

Downstream sequence

acaaaagatcaatgaaacaaaatggttttttgaaaagttaaacaaaatttacaaacctttagccagactaagaagaaaaaaggagacacaaattaataaa