Basic Information
VIS ID
TVIS10006866
Fusion event
HBV-chr13 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
pre-core/core
Start
370
Integrated sequence
CAATTTTCTAGGGGGAGCACCCACGTGTCCTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAATTTGTCCTGGCTAT| |CGCTGGATGTGTCTGCGGCGTTTTATCATATTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCG
Host Sequence
Chromosome
chr13
Cytoband
q12.12
Reference genome
GRCh37/hg19
Start
23463774/22889635 (Hg38)
End
23463774/22889635 (Hg38)
Location type
Intronic
Target gene
LINC00621 ; LOC105370109
Nearest miRNA
hsa-mir-4499/Upstream/2455789; hsa-mir-1267/Downstream/1272781;
Nearest TSS
ENST00000623511/Upstream/679350; ENST00000575845/Downstream/26734;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/40878, chr13-CpG: 17/Downstream/7989
Nearby gene
BASP1P1(No orient, 7395)
Upstream sequence
taacttagaaaccgatgttactcatagattcccaacattgtataaaagaacattgtgcaactccctgccctgttctgtttctctgaccaccagtacatgg
Downstream sequence
agcccctgtcacgtaccccctgcttgctcaaatcaatcacgaccctttcatgtgaaatctttagcgttgtgagcccttaaaagggacagaaattgtgtac
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate