Basic Information
VIS ID
TVIS10006875
Fusion event
HBV-LOC107985342 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
C2
Reference genome
JQ688404
Region type
pre-core/core
Start
1840
Integrated sequence
TGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATC| |ATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCTTCTGTGG
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
54156038/53652784 (Hg38)
End
54156038/53652784 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
LOC107985342
Nearest miRNA
hsa-let-7e/Upstream/1370891; hsa-mir-10394/Downstream/13895;
Nearest TSS
ENST00000633603/Upstream/20728; ENST00000597619/Downstream/109177;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3797, chr19-CpG: 23/Downstream/115702
Nearby gene
DPRX
Upstream sequence
taaggttccataaaacagaaaaagaatttcctttgtgatgccgcaggcttggccctcaggactatagtgtggcaagcagagtcactaggaccacctgggc
Downstream sequence
aaagggaacctagaagcctggcatgctggcaaaaggtaaagtatttcttaccaattagactgtggcccctctgtgcaaactggttagatgaacggtaaaa
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate