VISDB Viral Integration Site DataBase

VIS ID

TVIS10006887

Fusion event

HBV-MPPED1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

C2

Reference genome

Region type

Polymerase,S

Start

474

Integrated sequence

GGATGTGTCTGCGGCGTTTTATCATATTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTACCAAGGTATGTTGCCCGTTTG| |TCCTCTACTTCCAGGAACATCAACTACCAGCACGGGACCATGCAAGACCTGCACGATTCCTGCTCAAGGAACCTCTATGTTTCCCTCTTGTTGCTGTACA

Chromosome

chr22

Cytoband

q13.2

Reference genome

Start

End

43847861/43451961 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1238-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-27a-5p ; hsa-mir-6781-5p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-6131 ; hsa-mir-7152-3p ; hsa-mir-378g ; hsa-mir-4638-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-1281/Upstream/1528664; hsa-let-7a-3/Downstream/1748993;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/16719, chr22-CpG: 53/Downstream/360106

Upstream sequence

GTTGTCACATTGTTGGAGGTTTTCCCGCCTCCATGCCTTTCTTGTGTGGGCTGCTCCTGCCGGAGTGCCAATCCTGACTGCCTAGGGAGCTGCTGTCCAC

Downstream sequence

TATGGATACCTGTTTCTGTAGTTTCTGTGATCACCTCCCTATATttttctttttttctttctttttttttttttgaaatggagtcttgctctgttgccca