VISDB Viral Integration Site DataBase

VIS ID

TVIS10006891

Fusion event

HBV-MPPED1 integration

Validated

Yes

Detection method

Alu PCR and sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2015

PubMed ID

Virus name

HBV

Subtype

B2

Reference genome

Region type

Polymerase

Start

1219

Integrated sequence

CTAAGTAAACAGTATCTGAACCTTTACCCCGTTGCTCGGCAACGGCCTGGTCTGTGCCAAGTGTTTGCTGACGCAACCCCCACTGGTTGGGGCTTGGCCA| |TAGGCCATCAGCGCATGCGTGGAACCTTTGTGTCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGGGCAAA

Chromosome

chr22

Cytoband

q13.2

Reference genome

Start

End

43847856/43451956 (Hg38)

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1238-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-27a-5p ; hsa-mir-6781-5p ; hsa-mir-7162-5p ; hsa-mir-516b-3p ; hsa-mir-516a-3p ; hsa-mir-6131 ; hsa-mir-7152-3p ; hsa-mir-378g ; hsa-mir-4638-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p

Nearest miRNA

hsa-mir-1281/Upstream/1528659; hsa-let-7a-3/Downstream/1748998;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/16714, chr22-CpG: 53/Downstream/360111

Upstream sequence

GGGCAGTTGTCACATTGTTGGAGGTTTTCCCGCCTCCATGCCTTTCTTGTGTGGGCTGCTCCTGCCGGAGTGCCAATCCTGACTGCCTAGGGAGCTGCTG

Downstream sequence

TCCACTATGGATACCTGTTTCTGTAGTTTCTGTGATCACCTCCCTATATttttctttttttctttctttttttttttttgaaatggagtcttgctctgtt