Basic Information
VIS ID
TVIS10006892
Fusion event
HBV-LOC107986952 integration
Validated
Yes
Detection method
Alu PCR and sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2015
PubMed ID
25627239
Virus Sequence
Virus name
HBV
Subtype
B2
Reference genome
JQ688405
Region type
Polymerase,S
Start
460
Integrated sequence
TCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTGCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGT| |ATGTTGCCCGTTTGTCCTCTAATTCCAGGATCATCAACAACCAGCACCGGACCATGCAAAACCTGCACAACTCCTGCTCAAGGAACCTCTATGTTTCCCT
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
77491248/76579013 (Hg38)
End
77491248/76579013 (Hg38)
Location type
Intronic
Target gene
LOC107986952
Nearest miRNA
hsa-mir-124-1/Upstream/1873266; hsa-mir-10400/Downstream/387755;
Nearest TSS
ENST00000518652/Upstream/172359; ENST00000523885/Downstream/36015;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1170824, chr8-CpG: 59/Downstream/103007
Upstream sequence
aaaagcattgtatttctccacagccttgccagcatctattgcttcttgacatcttaatgagtgtcattctgattggcatgagatggtatctcattgtgat
Downstream sequence
CGGATAGAAAAATGTGTGAGACTGACAAAATATCCACAGTCTGTAACCTCTATTGGAAAAGGCTTTGATTACAGTAAAATTACACAAAAATGTGTCATTA
Reference
Yan, H., et al. Characterization of the genotype and integration patterns of hepatitis B virus in early- and late-onset hepatocellular carcinoma. Hepatology ,2015,61(6): 1821-1831.
Curate